Cardiovascular, metabolic and renal diseases

Cardiovascular, metabolic and renal diseases are closely interconnected chronic conditions that share common risk factors and pathophysiological pathways. Metabolic disorders, particularly lipid abnormalities such as elevated cholesterol and triglycerides,contribute to atherosclerosis development and increased thrombotic risk. Chronic kidney diseases, such as IgA nephropathy, are commonly associated with metabolic disturbances including dyslipidemia and enhanced thrombotic risk, which contribute to increased cardiovascular complications. Studies indicate that approximately 60%-80% of chronic kidney disease patients are diagnosed with HTG. The resultant dyslipidemia further exacerbates renal damage. Triglyceride levels exceeding 200 mg/dL in patients with chronic kidney disease are associated with a 2.3-fold increased risk of renal function decline.